Organ distribution of asialo-red blood cell ghosts: an attempt at targeting to the liver.
نویسندگان
چکیده
We investigated the organ distribution of four types of red blood cells (RBC) preparations: native RBC, asialo-RBC, native ghosts and asialo-ghosts. Intravenously injected asialo-ghosts were rapidly removed from the blood stream and accumulated mainly in the liver 120 min after the injection. Our results suggest that asialo-ghosts are a simple and effective carrier for targeting of drugs to the liver.
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ورودعنوان ژورنال:
- Acta medica Okayama
دوره 40 1 شماره
صفحات -
تاریخ انتشار 1986